Turkish Journal of Physical Medicine and Rehabilitation 2001 , Vol 47 , Num 6

Postmenopozal Osteoporozda Yüksek Kolesterol Düzeyi ile Kemik Mineral Yoğunluğunun İlişkisi

İbrahim Şenocak 1 ,Lale Cerrahoğlu 2 ,Mehmet Tuncay Duruöz 3
1 Celal Bayar Üniversitesi Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Manisa
2 Celal Bayar Üniversitesi Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Manisa, Türkiye
3 Celal Bayar Üniversitesi, Tıp Fakültesi Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Manisa

Abstract: The Relation Between High Cholesterol Level and Bone Mineral Density in Postmenauposal Osteoporosis.


Background: The relation between the cardiovascular risk factors and osteoporosis is well known.


Objective: To assess the femoral and lumbar BMD (by DXA) in postmenopausal osteoporotic women (PMO) with not high (<240 mg/dl) and high cholesterol (?240 mg/dl) levels.


Methods: Postmenopausal osteoporotic women according to WHO criteria, without antilipid treatment and sedentary life history were recruited randomly. Subjects classified as high cholesterol level and not high cholesterol leveled patients. Cholesterol level ?240 mg/dl accepted hypercholesterolemia. The femur neck, Ward’s triangle, trochanter, L1-L4 vertebras and L3 lateral Bone Mineral Densities (BMD) of each patient were assessed . The relation between groups was assessed by Mann-Whitney U test. P<0.05 was significant.


Results: Thirty-three PMO women (11 with high cholesterol) were taken into the study. There were not significant relation between the ages and BMD of both groups (similar groups). The relations between BMD of women with normal and high cholesterol levels were not significant at all measured regions.


Conclusion: There is no significant relation between BMD level and hypercholesterolemia in PMO women.

Keywords : Postmenauposal osteoporosis, hypercholesterolemia, bone mineral density