Turkish Journal of Physical Medicine and Rehabilitation 2001 , Vol 47 , Num 6
Omurilik Hasarlı Hastalarda Derin Ven Trombozu Profilaksisi ile Alınan Sonuçlar
Rıdvan Alaca 1 ,Bilge Yılmaz 2 ,A. Salim Göktepe 3 ,Haydar Möhür 3 ,Şükrü Gündüz 4
1 Gülhane Askeri Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Türk Silahlı Kuvvetleri Rehabilitasyon Merkezi, Ankara, Türkiye
2 Gülhane Askeri Tıp Akademisi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Türk Silahlı Kuvvetleri Rehabilitasyon Merkezi, Ankara, Türkiye
3 Gulhane Military Medical Academy, Department of Physical Medicine and Rehabilitation, Ankara, Turkey
4 Gülhane Askeri Tıp AKademisi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Ankara

The Results of Prophylaxis for Deep Vein Thrombosis in Patients With Spinal Cord Injury Deep vein thrombosis is one of the major causes of mortality and morbidity in patients with spinal cord injury. This retrospective study was performed on 70 patients admitted to GATA Department of Physical Medicine and Rehabilitation in the period between 1998-2000, with the aim to evaluate the efficacy of different prophylactic anticoagulant therapies in patients with spinal cord injury. The prophylaxis regimens used in those patients were; enoxaparin (n=43), warfarin (n=20), unfractionated heparin (n=2) and aspirin (n=5). Patients were investigated for deep vein thrombosis with serial doppler ultrasonography screenings at the admission and for 3 months when needed. Eight patients receiving warfarin and 7 patients receiving enoxaparin developed deep vein thrombosis. Only one patient receiving enoxaparin had a non-fatal pulmonary embolism. The bleeding rate was 25% at warfarin group and 18,6% at enoxaparin group. Statistical analysis of data obtained revealed that enoxaparin is superior to warfarin in prevention of deep vein thrombosis in patients with spinal cord injury (t=3,4; p<0,05). When we assess deep vein thrombosis and the bleeding together, enoxaparin compares favourably with warfarin again (t=2,09; p<0,05).

Keywords : Spinal cord injury, deep vein thrombosis, prophylaxis