Turkish Journal of Physical Medicine and Rehabilitation 2005 , Vol 51 , Num 1
Sclerosing Multiple Myeloma (Report of a Case)
Berrin Albayrak 1 ,Serap Yücel 2 ,Leyla Kılıç Atakanlı 1 ,Aliye Yıldırım 3 ,Nilnur Konuralp 1 ,Mehmet Hayri Özgüzel 4
1 SSK Okmeydanı Eğitim ve Araştırma Hastanesi Fizik Tedavi ve Rehabilitasyon Kliniği, İstanbul
2 SSK Okmeydanı Eğitim ve Araştırma Hastanesi İç Hastalıkları Hematoloji Ünitesi, İstanbul
3 Okmeydanı Eğitim ve Araştırma Hastanesi Fizik Tedavi ve Rehabilitasyon Kliniği, İstanbul
4 Sağlık Bakanlığı Okmeydanı Eğitim ve Araştırma Hastanesi, Fizik Tedavi ve Rehabilitasyon Kliniği, İstanbul

Myeloma, multiple myeloma or plasmacytoma is a malignant tumour originating from plasma cells that synthesize immunoglobulin in abnormal amount and invade the bone marrow. Multiple myeloma constitutes 27% of whole bone tumours and with this ratio it is the most common malign tumour of the bone. Bone involvements with localized or extensive musculoskeletal pain are characteristic. Multiple myeloma is a rare  but important pathology that must be considered in differential diagnosis of patients admitting to physical therapy outpatient clinics with nonspecific bone pain or artralgia. We examined a rare, non-secretory type multiple myeloma case that we had detected sclerotic bone lesions besides ordinary lytic lesions, with respect to demonstrative musculoskeletal system involvement. 

Keywords : Musculoskeletal pain, non-secretuar, sclerosing, multiple myeloma