Turkish Journal of Physical Medicine and Rehabilitation 2007 , Vol 53 , Num 2

The Role of Oxidative Stress in Rheumatic Diseases

Salih Özgöçmen 1
1 Erciyes Üniversitesi Tıp Fakültesi Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Romatoloji Bilimdalı, Kayseri, Türkiye

Reactive oxygen species and free radicals play important roles in physiologic and pathologic processes in the body. Data on the role of oxidative stress in the pathophysiology of inflammatory cascade and rheumatic diseases continues to accumulate. In this mini review oxidative stress mechanisms and new advances in the role of oxidative stress in the pathophysiology of rheumatic diseases have been briefly summarized.

Keywords : Free radicals, oxidative stress, rheumatic diseases